Active zone plasticity couples sleep need to presynaptic hypophosphorylation (opens in new tab)

Proceedings of the National Academy of Sciences, Volume 123, Issue 24, June 2026. SignificanceSynaptic plasticity has been causally linked to homeostatic sleep regulation. However, how synaptic plasticity governs the dynamic accumulation and dissipation of sleep pressure remains elusive. Using synapse-enriched proteomics and phospho-...