Correction to: Nature https://doi.org/10.1038/s41586-025-09389-x Published online 13 August 2025
During the typesetting process, a number of minor errors occurred which were not present in the peer-reviewed version or the provided source data. None of these mistakes affects any scientific conclusions and are corrected here.
During typesetting, incorrect chemical structures were copied into the graphs of Fig. 2e,f, where in Fig. 2e, a structure for 4OH-E2 appeared instead of 17β-estradiol, and in Fig. 2f, in the 2OH-E2 structure, upper left, “H” originally appeared instead of “HO.” In Fig. 2o,p, for Sham and IRI OVX mice, the labels now reading “n = 6” originally read “n = 2” and “n = 5,” respectively, while in Fig. 2q, the n…
Correction to: Nature https://doi.org/10.1038/s41586-025-09389-x Published online 13 August 2025
During the typesetting process, a number of minor errors occurred which were not present in the peer-reviewed version or the provided source data. None of these mistakes affects any scientific conclusions and are corrected here.
During typesetting, incorrect chemical structures were copied into the graphs of Fig. 2e,f, where in Fig. 2e, a structure for 4OH-E2 appeared instead of 17β-estradiol, and in Fig. 2f, in the 2OH-E2 structure, upper left, “H” originally appeared instead of “HO.” In Fig. 2o,p, for Sham and IRI OVX mice, the labels now reading “n = 6” originally read “n = 2” and “n = 5,” respectively, while in Fig. 2q, the number of Sham OVX mice, now reading “n = 5,” appeared originally as “n = 2.”
At the end of page 1011, Extended Data Fig. 2a–c was incorrectly referred to as “Extended Data Fig. 3a–c.” At the top of page 1012, Extended Data Fig. 2d and Extended Data Fig. 2e were incorrectly referenced as “Extended Data Fig. 3d” and “Extended Data Fig. 3e.” At the top of the second column on page 1012, Extended Data Fig. 3a–m was incorrectly referred to as “Extended Data Fig. 4a–m.” On page 1014, Fig. 2j–m and 2n–q were incorrectly referenced as “Fig. 2k–n” and “Fig. 2o–r,” respectively.
The text on page 1012 refers to the effects of testosterone in Supplementary Figs. 3 and 4. However, due to an error that occurred during the transfer of files from Extended Data to Supplementary Information, the supplied file duplicated plots from Extended Data Fig. 3. The correct Supplementary Fig. S3, as present in the peer reviewed manuscript and in the source data, now appears in the Supplementary Information alongside the article.
In Extended Data Fig. 2b,c, the “male” and “female” labels were swapped during the typesetting process. The figure legend now correctly refers to both cortical and medullary renal sections. During typesetting, the label on the y-axis of Extended Data Fig. 2c was incorrectly modified to “tubular damage score cortex” instead of “tubular damage score medulla” as in the peer-reviewed version. The correct Extended Data Fig. 2 is now presented in the article.
In Extended Data Fig. 4, some panels in d and e of the representative flow cytometry plots were incorrect. The single data points in the bar graphs quantifying the experiments were correct at all times and the primary data of the experiment were included at all times. The correct panels now appear in Extended Data Fig. 4.
Regarding the corrected plot of Extended Data Fig. 4e, NIH3T3 cells were pretreated with 10 µM 17 β-oestradiol for 16 hours before inducing ferroptosis by addition of 1.3 µM RSL3. Flow cytometry for annexin V / 7-AAD was used as a readout to quantify cell death at indicated timepoints, with 1 µM Fer-1 serving as a protection control.
The text, figures and Supplementary Information have now been amended in the HTML and PDF versions of the article.
Author information
Author notes
These authors contributed equally: Wulf Tonnus, Francesca Maremonti, Shubhangi Gavali
Authors and Affiliations
Division of Nephrology, Department of Internal Medicine 3, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany
Wulf Tonnus, Marlena Nastassja Schlecht, Karolin Flade, Natalie Bethe, Anne Brucker, Jorunn Naila Becker, Mirela Tmava & Christian Hugo 1.
Department of Medicine V, University Medical Centre Mannheim, University of Heidelberg, Mannheim, Germany
Francesca Maremonti, Shubhangi Gavali, Florian Gembardt, Nadja Leinung, Claudia Meyer, Melika Katebi, Anushka Ray, Louisa M. S. Gerhardt & Andreas Linkermann 1.
Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany
Alexia Belavgeni, Sofia Traikov & Mirko Peitzsch 1.
Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany
Sofia Traikov & Andrej Shevchenko 1.
Chair of Organic Chemistry, Technische Universität Dresden, Dresden, Germany
Anne Haag & Bernd Plietker 1.
Division of Redox Regulation, German Cancer Research Center (DKFZ), DKFZ-ZMBH Alliance, Heidelberg, Germany
Danny Schilling & Tobias P. Dick 1.
Faculty of Biosciences, Heidelberg University, Heidelberg, Germany
Danny Schilling & Tobias P. Dick 1.
Center of Membrane Biochemistry and Lipid Research, University Hospital and Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
Sider Penkov & Maria Fedorova 1.
Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Ontario, Canada
Melodie Mallais & Derek A. Pratt 1.
Equipe Labellisée Ligue Contre le Cancer, Institut Curie, CNRS, INSERM, PSL Research University, Paris, France
Christine Gaillet & Raphaël Rodriguez 1.
Division of Tumor Metabolism and Microenvironment, German Cancer Research Center (DKFZ), Heidelberg, Germany
Lisa Schlicker & Almut Schulze 1.
Institute of Physiology, Christian-Albrecht-University Kiel, Kiel, Germany
Nina Himmerkus 1.
Max Planck Institute for Polymer Research, Mainz, Germany
Uladzimir Barayeu 1.
Service of Rheumatology, Department of Musculoskeletal Medicine, Centre Hospitalier Universitaire Vaudois, University of Lausanne, Lausanne, Switzerland
Sonia Nasi 1.
Clinic for Urology, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany
Juliane Putz 1.
Laboratories of Reproductive and Developmental Toxicology, NIEHS, National Institutes of Health, Research Triangle Park, NC, USA
Kenneth S. Korach 1.
Renal Division, Montefiore Medical Center, Albert Einstein College of Medicine, New York, NY, USA
Joel Neugarten & Ladan Golestaneh 1.
Institute of Pathology, University Hospital of Cologne, Cologne, Germany
Jan Ulrich Becker 1.
Division for Nephrology, University of Michigan Medical Center, Ann Arbor, MI, USA
Joel M. Weinberg 1.
Institute of Metabolism and Cell Death, Helmholtz Zentrum München, Neuherberg, Germany
Svenja Lorenz, Bettina Proneth & Marcus Conrad 1.
Chair for Molecular Animal Breeding and Biotechnology, Gene Center and Department of Veterinary Sciences, LMU Munich, Munich, Germany
Eckhard Wolf 1.
Center for Innovative Medical Models (CiMM), LMU Munich, Oberschleißheim, Germany
Eckhard Wolf 1.
German Center for Diabetes Research (DZD), Neuherberg, Germany
Eckhard Wolf 1.
Department of Internal Medicine 3, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany
Stefan R. Bornstein & Andreas Linkermann 1.
Diabetes and Nutritional Sciences, King’s College London, London, UK
Stefan R. Bornstein 1.
Center for Regenerative Therapies, Technische Universität Dresden, Dresden, Germany
Stefan R. Bornstein 1.
Paul Langerhans Institute Dresden of Helmholtz Centre Munich at University Clinic Carl Gustav Carus of TU Dresden Faculty of Medicine, Dresden, Germany
Stefan R. Bornstein 1.
Division of Nephrology, Department of Medicine, Albert Einstein College of Medicine, New York, NY, USA
Andreas Linkermann
Authors
- Wulf Tonnus
- Francesca Maremonti
- Shubhangi Gavali
- Marlena Nastassja Schlecht
- Florian Gembardt
- Alexia Belavgeni
- Nadja Leinung
- Karolin Flade
- Natalie Bethe
- Sofia Traikov
- Anne Haag
- Danny Schilling
- Sider Penkov
- Melodie Mallais
- Christine Gaillet
- Claudia Meyer
- Melika Katebi
- Anushka Ray
- Louisa M. S. Gerhardt
- Anne Brucker
- Jorunn Naila Becker
- Mirela Tmava
- Lisa Schlicker
- Almut Schulze
- Nina Himmerkus
- Andrej Shevchenko
- Mirko Peitzsch
- Uladzimir Barayeu
- Sonia Nasi
- Juliane Putz
- Kenneth S. Korach
- Joel Neugarten
- Ladan Golestaneh
- Christian Hugo
- Jan Ulrich Becker
- Joel M. Weinberg
- Svenja Lorenz
- Bettina Proneth
- Marcus Conrad
- Eckhard Wolf
- Bernd Plietker
- Raphaël Rodriguez
- Derek A. Pratt
- Tobias P. Dick
- Maria Fedorova
- Stefan R. Bornstein
- Andreas Linkermann
Corresponding author
Correspondence to Andreas Linkermann.
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Tonnus, W., Maremonti, F., Gavali, S. et al. Publisher Correction: Multiple oestradiol functions inhibit ferroptosis and acute kidney injury. Nature (2026). https://doi.org/10.1038/s41586-026-10148-9
Published: 21 January 2026
Version of record: 21 January 2026
DOI: https://doi.org/10.1038/s41586-026-10148-9