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Computational Biology
🧬 Computational Biology
Protein Folding, Genomics, AlphaFold, Bioinformatics, Drug Targets
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67
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ms
A
Drug-Target
Specificity Foundation Model for
Off-target
Prediction, Repurposing, and Generative Design
💊
Drug Discovery
Content type:
Academic
biorxiv.org
·
2d
2 days ago
Actions for A Drug-Target Specificity Foundation Model for Off-target Prediction, Repurposing, and Generative Design
How AI is quietly changing what we think the human mind is
🤖
Anthropic AI
bigthink.com
·
5d
5 days ago
Actions for How AI is quietly changing what we think the human mind is
Structural motif search across the
protein
universe with Folddisco
🧠
tinygrad
Content type:
Academic
nature.com
·
6d
6 days ago
Actions for Structural motif search across the protein universe with Folddisco
Cells have a secret power line: How the nucleus gets its own private energy supply from mitochondria
🧪
rdkit
phys.org
·
1d
1 day ago
Actions for Cells have a secret power line: How the nucleus gets its own private energy supply from mitochondria
Proteomics-constrained
deconvolution reveals spatial cell-type programs in tumours
🧪
rdkit
Content type:
Academic
biorxiv.org
·
6d
6 days ago
Actions for Proteomics-constrained deconvolution reveals spatial cell-type programs in tumours
Mitochondria directly interact with the nuclear pore complex
🔬
Biotech
Content type:
Academic
nature.com
·
1d
1 day ago
Actions for Mitochondria directly interact with the nuclear pore complex
VLab4Mic: prediction of structural resolvability in super-resolution microscopy
🧠
tinygrad
Content type:
Academic
biorxiv.org
·
6d
6 days ago
Actions for VLab4Mic: prediction of structural resolvability in super-resolution microscopy
First nonrepeating
biological
clock discovered in C. elegans guides growth
🔬
Biotech
phys.org
·
4d
4 days ago
Actions for First nonrepeating biological clock discovered in C. elegans guides growth
SIRT7 regulates dosage compensation and safeguards the female X chromosome
💊
Drug Discovery
Content type:
Academic
nature.com
·
1d
1 day ago
Actions for SIRT7 regulates dosage compensation and safeguards the female X chromosome
DeltaMut: An Integrative Database of
AlphaFold2-Derived
Missense Variant Structures
🧪
rdkit
Content type:
Academic
biorxiv.org
·
5d
5 days ago
Actions for DeltaMut: An Integrative Database of AlphaFold2-Derived Missense Variant Structures
CLASPP: A unified model for predicting post-translational modifications
🧪
rdkit
Content type:
Academic
biorxiv.org
·
3d
3 days ago
Actions for CLASPP: A unified model for predicting post-translational modifications
Corylin promotes healthy aging via RAGA–mTOR suppression and sex-dependent activation of SIRT3
🔬
Biotech
Content type:
Academic
nature.com
·
1d
1 day ago
Actions for Corylin promotes healthy aging via RAGA–mTOR suppression and sex-dependent activation of SIRT3
Divergent Loop Architecture Shapes Pocket2 Variation in Shark Legumains
💊
Drug Discovery
Content type:
Academic
biorxiv.org
·
3d
3 days ago
Actions for Divergent Loop Architecture Shapes Pocket2 Variation in Shark Legumains
De Novo Design and
Computational
Validation of a High-Affinity Peptide Inhibitor
Targeting
the HPV E1-E2 Interface
🧪
rdkit
Content type:
Academic
biorxiv.org
·
6d
6 days ago
Actions for De Novo Design and Computational Validation of a High-Affinity Peptide Inhibitor Targeting the HPV E1-E2 Interface
Bots are scraping open data — how should researchers respond?
🧠
tinygrad
Content type:
Academic
nature.com
·
3d
3 days ago
Actions for Bots are scraping open data — how should researchers respond?
Inhibition of the QPCT–PDIA4 axis rescues ΔF508 and N1303K CFTR in cystic fibrosis
💊
Drug Discovery
Content type:
Academic
nature.com
·
2d
2 days ago
Actions for Inhibition of the QPCT–PDIA4 axis rescues ΔF508 and N1303K CFTR in cystic fibrosis
Megalin (LRP2), prenatal betamethasone, and injury susceptibility in the developing kidney
🤰
pregnancy
Content type:
Academic
biorxiv.org
·
3d
3 days ago
Actions for Megalin (LRP2), prenatal betamethasone, and injury susceptibility in the developing kidney
Single-cell spatial pharmacobiology for imaging antibody-based therapies in solid tumors
💊
Drug Discovery
Content type:
Academic
nature.com
·
3d
3 days ago
Actions for Single-cell spatial pharmacobiology for imaging antibody-based therapies in solid tumors
Multi-omic data fusion reveals the in vivo enzyme kinetics of Vibrio natriegens at the
genome-scale
🧪
rdkit
Content type:
Academic
biorxiv.org
·
6d
6 days ago
Actions for Multi-omic data fusion reveals the in vivo enzyme kinetics of Vibrio natriegens at the genome-scale
Resolving rapid cell-surface
proteome
remodelling in intact neural circuits
🧪
rdkit
Content type:
Academic
nature.com
·
6d
6 days ago
Actions for Resolving rapid cell-surface proteome remodelling in intact neural circuits
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