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Nuclear export of R-loop by the DDX1 and XPO1 complex promotes senescence-associated secretory phenotype and inflammaging (opens in new tab)

Covered by 4 sources including Refractor, Medical Xpress

Covered in 4 articles

Existing drug blocks newly discovered aging and inflammation pathway

Medical Xpress·

Study identifies a new cause of age-related inflammation, suggesting promising treatment pathway

Lifespan Research Institute·

A Transcriptional Failure Leads to Systemic Inflammation

Age-Related Inflammation Linked to R-Loop Nucleic Acids, Opens Therapies