Repeated mRNA covid vaccinations may make more diverse and stronger T cell response, potentially better protecting against unseen and broader range of covid var...
science.org·10h
📊Embeddings
Direct Instruction (DI) provides a clear path for evaluating instructional design. Here are 20 rules and recommendations for effective programs:
threadreaderapp.com·7h
🪄Prompt Engineering
Next.js is not a good fit for vibe engineering
fabianlindfors.se·3h·
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👨‍💻Software development practices
Loyca.ai – An open-source, local-first AI assistant with contextual awareness
github.com·4h·
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🏗️LLM Infrastructure
Datastar Response to Allegations
data-star.dev·43m·
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🌟Datastar
OCaml 5.4 Release: New Features, Fixes, and More
tarides.com·15h·
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💻Programming languages
Bride surprises new husband with an RTX 5090 on wedding day — Chinese number slang reveals surprise gift
tomshardware.com·10h
⚙️Mechanical Sympathy
Breakthrough mirror-image nanopores open door to new biomedical applications
phys.org·6h
🧪Glutamate
Transferring Colleges: When And How To Make The Move
nordot.app·15h
🐻Brown University
Vibing a Non-Trivial Ghostty Feature
simonwillison.net·6h
🪄Prompt Engineering
Academic Chat with Murat and Aleksey: 5 Cs of the Invisible Curriculum.
charap.co·22h
🎓Advanced content
Substack Doesn't Want You to Leave
aaronrosspowell.com·7h·
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📡RSS
Cambridge University launches project to rescue data trapped on old floppy disks
tomshardware.com·4h
⏳Tech History
Framework under fire for Omarchy/DHH/Hyprland support?
crimier.github.io·12h·
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🏝️Islands Architecture
Show HN: ObolusFinanz – Simple finance tools (German tax and investment)
obolusfinanz.de·13h·
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🐯TigerBeetle
Weeknotes: Oct. 4-10, 2025
tracydurnell.com·16h
🏝️Islands Architecture
Show HN: We used LZMA to encode data into a URL
standardsapplied.com·4h·
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📊Vector Databases
Windows Subsystem for FreeBSD (WSFB)
github.com·15h·
Discuss: Lobsters, Hacker News
🏠Self-hosting
The Electret Preamp You Might Need
hackaday.com·14h
📖E-Ink
Laion, the dataset behind Stable Diffusion (2023)
deeplearning.ai·17h·
Discuss: Hacker News
🏗️LLM Infrastructure