Members of President Donald Trump’s cabinet, including Energy Secretary Chris Wright, Commerce Secretary Howard Lutnick, Chief of Staff Susie Wiles, Treasury Secretary Scott Bessent and Secretary of State Marco Rubio, listen to Trump address the World Economic Forum (WEF) in the Davos Congress Center on Jan. 21, 2026 in Davos, Switzerland.

Chip Somodevilla | Getty Images

The U.S. is looking increasingly isolated when it comes to its global geopolitical and trade relationships as allies reassess their ties to the world’s largest economy and consider going it alone.

The new year has seen a number of nations and power blocs forging ahead with relationship resets, closer commercial ties and trade partnerships, sidelining a more hostile and volatile U.S. They include China’s "[pre…

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