Video + notes on upgrading a Datasette plugin for the latest 1.0 alpha
simonwillison.net·3d
🔓Binary Exploitation
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Organism-Specific Sequence Motifs Link Ribosomal RNAs to Brain Disorders
🧬Computational Biology
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ID verification laws are fueling the next wave of breaches
bleepingcomputer.com·1d
🔒Digital Privacy
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Elfeed Curate Update: Two new features
📡RSS
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Playing With My Son: An experiment in forced nostalgia, questionable parenting
🕹️Retro Gaming
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Automated Conformational Sampling & Scoring via Hybrid Monte Carlo-Gradient Techniques for Lead Optimization
🧬Computational Biology
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I've been trying to make a real production service that uses LLM and it turned into a pure agony. Here are some of my "experiences".
🦙Ollama
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Using Claude Code heavily for 6+ months: Why faster code generation hasn't improved our team velocity (and what we learned)
🎭Program Synthesis
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Agentic Bitcoin24
💰TigerBeetle
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What Is a Lua Module in Roblox in 2025?
🦀Rust Macros
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Tech With Tim: OpenAI’s New Agent Builder is Insane - Full Tutorial
💬Prompt Engineering
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