Author(s): Justyna P. Zwolak and Jacob M. Taylor A promising platform for quantum computing consists of arrays of quantum dots. However, operating these devices presents a challenging control problem, since the location of the dots and the charges they contain must be reliably and reproducibly matched with the gate voltages. This Colloquium explains how automated control protocols that make use of machine learning techniques can succeed in systems where heuristic control is not feasible. [Rev. Mod. Phys. 95, 011006] Published Fri Feb 17, 2023