Americans born in the 1960s and early 1970s are reporting higher levels of loneliness and depression than people from earlier generations. They are also showing declines in memory and physical strength. These patterns are unusual when compared with other wealthy nations. In many peer countries, especially in Nordic Europe, measures of midlife health and well-being have improved rather than worsened.

To better understand why the United States stands out, psychologist Frank J. Infurna of Arizona State University and his colleagues analyzed survey data from 17 countries. Their goal was to explain why trends in U.S. midlife health differ so sharply from those seen elsewhere.

"The real midlife crisis in America isn’t about lifestyle choices or sports cars. It’s about juggling work,…

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