🔬 Seurat - pfh · Scour

An integrative omics-guided druggability analysis of VCX2 in hepatocellular carcinoma using Peruvian natural products 🔥ComplexHeatmap

frontiersin.org·2d

Gene regulatory networks define human airway epithelial cell types and their distinct responses to type I interferon 📊Differential Expression

biorxiv.org·6d

Identifying maximally informative signal-aware representations of single-cell data using the information bottleneck 📦Pseudobulk

A single-cell RNA sequencing dataset of cardiac aging in African Turquoise Killifish 📐edgeR

scHelix: Asymmetric Dual-Stream Integration via Explicit Gene-Level Disentanglement 📦Pseudobulk

Redundant and distinct mechanisms suppress innate immune activation during SARS-CoV-2 infection 📊Differential Expression

journals.plos.org·14h

Lineage priming and cell type proportioning depends on the interplay between stochastic and deterministic factors 🦠Whole cell model

elifesciences.org·2d

Decoding and steering spatially resolved cellular dynamics 🗺️Spatial Transcriptomics

link.springer.com·5d

Global cell-state and gene-program representations reveal conserved and context-specific perturbation responses of cells 🗺️UMAP

biorxiv.org·1d

Ferroptosis-pyroptosis crosstalk signature as prognostic biomarkers and therapeutic targets in sepsis-induced ARDS 🔥ComplexHeatmap

frontiersin.org·5d

Spatial proteomic analysis in human Alzheimer’s disease brains enables identification of microenvironment-dependent microglial cell states 🔬Single-cell RNA-Seq

BRIDGE-GRN: Role-Aware Bi-Tower Graph Learning with Cross-View Contrast for Directed Gene Regulatory Network Inference 🗺️Network Visualization

biorxiv.org·5d

Systematic analysis of programmed cell death–related genes in sepsis reveals immune heterogeneity and enables patient stratification 📊Differential Expression

frontiersin.org·1d

HELIX: a scalable model for predicting context-dependent regulation of RNA splicing and isoform usage 🧬RNA-Seq

·1d

Disagreement between demultiplexing methods reveals structured cell quality gradients in multiplexed single-cell data 🔬Single-cell RNA-Seq

biorxiv.org·6d

Less-relevant results

Editorial: AI in single-cell biology 🔬Single-cell RNA-Seq

frontiersin.org·1d

H3K9me3 controls epidermis morphogenesis by regulating RNA Pol II dynamics at developmental promoters and enhancers 🧬RNA-Seq

Deep Learning for Cross-Domain Spatial Transcriptomic Modeling of Tissue Repair 🗺️Spatial Transcriptomics

biorxiv.org·4d

cran2crux: automatically create CRUX ports for R-packages 🧬Bioconductor

biorxiv.org·6d

SpatialArtifacts: a computational framework for tissue artifact detection in spatial transcriptomics data 🗺️Spatial Transcriptomics

biorxiv.org·1d

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