BindCORE: Biophysical Ensemble Learning for Predicting Interaction Sites in Intrinsically Disordered Regions

bioRxiv · Aug 23 · 🤖 AI

Intrinsically disordered proteins and regions (IDPs/IDRs) mediate diverse cellular functions through binding segments whose functional properties are encoded in dynamic conformational ensembles rather than a single static state. Existing predictors of linear interacting peptides (LIPs) and molecular...