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A quantitative cell-based reporter links TDP-43 aggregation and dysfunction to define pathogenic mechanisms

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How does the cerebellum contribute to cognitive functions?

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Curvature of the Drosophila corneal lens depends on localized chitin secretion

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Why do we have so many different transcripts?

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Host jumps need not be common just because spillover is

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Distinct Cdc42 protein levels differentially regulate polarized growth and cell fusion in Schizosaccharomyces pombe

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Pharmacological and non-pharmacological methods of inducing wakefulness activate distinct neural populations in the mouse brain

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Pathogen host jump risk is not predicted by spillover rate, but rather by novelty

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Transcript diversity reflects deleterious RNA processing errors shaped by population size in metazoans

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Measures to strengthen international biosafety and biosecurity practices

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Thaliacean tunicates, vertebrate sisters regained lifelong mobility

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Fine-tuning ERK activity enables proliferation-differentiation balance during lineage specification of human embryonic stem cells

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Systematic identification of Salmonella T6SS effectors uncovers diverse new families and lipid-targeting activities

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The Rpd3 histone deacetylase is a critical regulator of temperature-mediated morphogenesis and virulence in the human fungal pathogen Histoplasma

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Engineered romidepsin biosynthetic pathways in Escherichia coli Nissle 1917 improve the efficacy of bacteria-mediated cancer therapy

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Comparative embryogenesis of two salp species reveals rogue development and evolutionary divergence from sessile tunicates

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Correction: Why PLoS Became a Publisher

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Eye movements reflect memory-related theta activity in the human brain

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Behavioral engagement facilitates auditory neuron responses beyond their receptive fields

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Non-peptide dysbiosis metabolites reprogram a peptide quorum-sensing receptor to induce sustained predation in beneficial streptococci

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