PLOS Biology journals.plos.org

Human brains construct individualized global rankings from identical few-shot learning input

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Altered salience network structure–function integration underlies the decline in cognitive flexibility during aging

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Bacteria producing the bioplastic polyhydroxybutyrate kill the nematode Caenorhabditis elegans

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Structural insights into subtype-specific agonist recognition by sphingosine-1-phosphate receptors

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Casein kinase 2-mediated phosphorylation of the splicing factor SF3B3 plays a key role in esophageal squamous cell carcinoma progression

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Maternal regulation of translation capacity across generations

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Dietary restriction shapes intergenerational ribosome abundance and early growth of Caenorhabditis elegans offspring

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A dual-threshold system relying on multiple c-di-GMP metabolic enzymes controls cell fate of a cyanobacterium

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Sleep strengthens successor representations of learned sequences in humans

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Correction: USP7 facilitates brain tumor survival upon glucose deprivation by regulating phosphofructokinase muscle-type nuclear translocation in mice

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The non-vesicular cholesterol transporter GRAMD1C is a pan-coronavirus antiviral target

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The time has come for big changes to improve research funding

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The m 6 Am methyltransferase PCIF1 promotes osteogenic differentiation of mesenchymal stem cells through stabilization of Wnt-related transcripts

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How the brain copes with bad times

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Emotion regulation success involves systematic gradient-based reconfigurations of large-scale activation patterns in the human brain

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Macrophages self-generate and refine chemotactic gradients during migration towards complement C5a

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Specificity and recognition of the ADP-ribosyl-ubiquitin modification in the DNA damage response

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Evolution of a truncated nucleocapsid protein enhances SARS-CoV-2 fitness by suppressing antiviral responses

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Aberrant dopaminergic activity during consolidation causes age-related memory generalization in Drosophila

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Evidence for genetically-based sperm discrimination in the vaginal tract of a primate species

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