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Editorial Note: A nonenzymatic dependency on inositol-requiring enzyme 1 controls cancer cell cycle progression and tumor growth

journals.plos.org5 min read
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Structural snapshots of the glucose-6-phosphate/phosphate exchange cycle

journals.plos.org9 min read
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The long horizon of animal study preregistration: Attitudes, barriers, and myths

journals.plos.org6 min read
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A survey of researchers’ attitudes to preregistration in animal research reveals multiple perceived barriers to adoption

journals.plos.org45+ min read
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Structural basis for substrate recognition and inhibition of human glucose-6-phosphate transporter SLC37A4

journals.plos.org30 min read
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Where next for structural bioinformatics?

journals.plos.org6 min read
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A desynchrony mechanism between events triggers a compensatory delay during Caenorhabditis elegans development

journals.plos.org45+ min read
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Cell type-specific Ca 2+ signals govern mouse seminiferous tubule physiology

journals.plos.org45+ min read
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Competing value signals impair reward-learning via dopaminergic mechanisms and increase exploration

journals.plos.org45+ min read
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Asymmetry in the evolution of the male and female germlines

journals.plos.org8 min read
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sept-1/zina-1 is an ancient toxin-antidote system in Caenorhabditis elegans

journals.plos.org45+ min read
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Clonal drift in the aging gut: Mapping the fate of stem cells over time

journals.plos.org7 min read
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Why biology must prioritize data reanalysis in the era of artificial intelligence

journals.plos.org10 min read
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Noise-invariant representations of sound emerge along the canonical cortical hierarchy

journals.plos.org45+ min read
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Comparative single-nucleus transcriptomics reveals asymmetric evolution of the Drosophila male and female germlines

journals.plos.org45+ min read
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Neuronal protein Sex-lethal modulates tRNA synthesis via the polymerase III subunit Polr3E in male Drosophila neurons

journals.plos.org45+ min read
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A high-resolution phenotypic screen identifies regulators of CNS axon diameter in zebrafish

journals.plos.org45+ min read
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Retrosplenial cortical reorganization during late adolescence introduces instability of contextual memory circuits

journals.plos.orgCovered by345+ min read
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Queuosine tRNA modification regulates translational adaptation and virulence of Leishmania mexicana

journals.plos.org45+ min read
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Competing speech streams are simultaneously represented in the human cortex during attention switching

journals.plos.orgHNCovered by645+ min read
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