Nature Aging · Scour

Hypoxia-induced autophagic degradation of HIF-1α attenuates cellular aging and extends mammalian lifespan

·

Somatic variants in microglia-like cells linked to Alzheimer’s disease pathology

·

Brain endothelial cell-derived extracellular vesicles (c-BEEVs) as a promising biomarker for brain vascular pathology and cognitive decline

·

Tissue softness unlocks regeneration

·

Mitigating the Hawthorne effect in aging research

·

The aging extracellular matrix as a missing link in senescent cell accumulation and persistence

·

Multimodal data analysis reveals asynchronous aging dynamics across female reproductive organs

·

Connecting fragmented aging research through the European Federation for Aging Research

·

Repurposing drugs for the prevention of vascular dementia using evidence from drug target Mendelian randomization

p21 + TREM2 + senescent macrophages fuel inflammaging and metabolic dysfunction-associated steatotic liver disease

Neuronal APOE4-induced early hippocampal network hyperexcitability in Alzheimer’s disease pathogenesis

nature.com··Hacker News

Astrocyte-based CAR immunotherapy against Alzheimer’s disease

·

Stem cell therapy might improve aging frailty

·

Extracellular vesicles derived from senescent hepatocytes drive pan-cancer metastasis in aging

·

Single-cell analysis of the human immune system reveals sex-specific dynamics of immunosenescence

·

The case for space as a model of accelerated aging

·

Exoproteome of calorie-restricted humans identifies complement deactivation as an immunometabolic checkpoint reducing inflammaging

Biological sex shapes divergent trajectories of immune aging

·

Log in to enable infinite scrolling