npj Systems Biology and Applications · Scour

A novel approach to quantify out-of-distribution uncertainty in Neural and Universal Differential Equations

Untargeted metabolomics reveals organism specific biomarkers of carbapenem resistance in Klebsiella pneumoniae and Escherichia coli

Decoding cellular population dynamics through mechanistic modelling and statistical data analysis

Molecular maps of diseases from omics data and network embeddings

Cell trajectory inference based on schrödinger problem and a mechanistic model of stochastic gene expression

Gene overexpression reduces inhibitory metabolites to enhance CHO cell growth and IgG1 production

Interpretable multitask model for clinical pathology image prediction and interpretation

Control of genes by self-organizing multicellular interaction networks

Supervised machine learning identifies impaired mitochondrial quality control in β-cells with development of type 2 diabetes

Emergence of Sprouty role from the signaling interplay of DUSP1 and DUSP4 interactions in NSCLC pathogenesis

tugMedi: simulator of cancer-cell evolution for personalized medicine based on the genomic data of patients

Inferring absolute counts from proportions by constraining multivariate normal distributions

Bacterial gene regulatory neural network as a biocomputing library of mathematical solvers

Interpreting MALDI imaging data for rare types of ampullary cancer using machine learning

CT-TADB predicts TAD boundaries without Hi-C by integrating DNA sequences and epigenomic features

Decoupling the chemical and physical origins of the seed spectral manifold in sorghum

A rule-based simulation model illuminates the role of asymmetric mitochondrial fission on beta-cell health

Flux sampling and graph neural networks for improved gene essentiality prediction in mammalian genome-scale metabolic models

Genetic basis of temporal variation in phenology in a woody perennial plant

Learning patient-specific spatial biomarker dynamics via operator learning for Alzheimer’s disease progression

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