Membrane-Associated Self-Assembly for Cellular Decision Making (opens in new tab)

arXiv:2505.17290v2 Announce Type: replace-cross Abstract: Cellular decision-making based on information received from the external environment is frequently initiated by transmembrane receptors. These receptors are known to propagate such information by triggering a series of irreversible, energy-consuming reactions. While this active mechanism ensures switch-like responses, here we show how spontaneous self-assembly of native 3D subunits on a two-dimensional substrate can similarly act as a ...