Collective gene dynamics leave signatures of decision landscapes in cell fate coordinates (opens in new tab)

arXiv:2506.04219v2 Announce Type: replace-cross Abstract: Multicellular organisms contain a wide variety of highly specialized cell types. The consistency and robustness of developmental trajectories suggest that complex gene regulatory networks effectively act as low-dimensional cell fate landscapes. Prior work inspired by dynamical systems theory argues that cell fate transitions fall into universal decision-making classes, but the theory connecting these geometric landscapes to high-dimens...