PyPeakRankR: Reproducible Peak-Level Feature Extraction for Regulatory Element Ranking (opens in new tab)

High-throughput chromatin accessibility assays such as ATAC-seq generate thousands of candidate regulatory elements (peaks), yet no standardized tool exists for assembling the diverse quantitative features needed to prioritize peaks for functional validation. Here we present PyPeakRankR, an open-source Python package that extracts peak-level features, namely BigWig signal summaries, GC content, PhyloP conservation scores, distribution moments (k...