Concept Alignment Contrast and Long-Short Prompt Memory for Test-Time Adaptation of SAM3 in Medical Image Segmentation (opens in new tab)

Concept segmentation models like Segment Anything Model 3 (SAM3) show strong generalization on natural images, yet their performance degrades in medical imaging due to the domain gap caused by different imaging principles and styles. Test-Time Adaptation (TTA) is essential for improving the testing performance by updating the model on the fly without annotations. However, existing vision-language TTA methods are mainly driven by image-level unce...