Graph-based analysis of inflammatory profiles in New Onset Refractory Status Epilepticus (NORSE) (opens in new tab)

Background and Objectives: Cryptogenic new-onset refractory status epilepticus (cNORSE) represents one of the most severe forms of status epilepticus, occurring in patients without prior neurological disease, and remaining of unknown aetiology despite extensive diagnostic evaluation. Emerging evidence supports a role for immune dysregulation in cNORSE; however, marked heterogeneity in inflammatory signatures has been reported, complicating the s...