Endeavor: Efficient PairHMM for Detection of DNA Variants in Genome-Scale Datasets (opens in new tab)

DNA variant calling represents a key operation in bioinformatics pipelines that aims at identifying genetic variants. Given an evidenced explosion in genomic data availability, there is an urgent need for a high-performant, portable and efficient solution for variant calling, which can further improve our understanding of genomic structure and genetic basis for complex diseases. In its most common formulation, the Pair Hidden Markov Model (PairH...