A 400-Plasmid Collection for Making Immune Cells from Scratch (opens in new tab)

Guiding a cell through differentiation to its eventual fate requires a precise recipe of molecular signals, with transcription factors (TFs) as the key ingredients. With the right combination of TFs, scientists can also reprogram cell identity in the lab. In immune cells, such reprogramming could be useful to treat cancer and autoimmune diseases — but only a handful of immune cell types have known TF recipes. The REPROcode platform from the was built to change that.