Meet FrustrAI-Seq: Proteome-Wide Frustration Profiling Without Structural Inputs (opens in new tab)

Proteins are remarkable molecules. They fold, bend, bind, and catalyze, all while balancing an internal tension that most biology textbooks barely mention. That tension has a name: local energetic frustration. And a new study from researchers at Helmholtz Munich, the Technical University of Munich, and the Barcelona Supercomputing Center has just made it dramatically easier […] The post appeared first on <a href="