Rational Design of Degrader with AI and MS technology #memo #journal (opens in new tab)

Targeted Protein Degrader (TPD) is one of the attractive modality of recent drug discovery area. As most of readers know that First TPD, ER degrader gains FDA approval in this year. TPD molecule induce PPI of POI and E3 ligase and degradation of POI. It is unique mechanism because chemical compounds can induce artificial degradation"Rational Design of Degrader with AI and MS technology #memo #journal"