Long COVID Persistence and Surveillance Gaps Across 58 US Hospitals | Infectious Diseases | JAMA Network Open (opens in new tab)

Question What is the true burden of chronic disease following COVID-19, and why does current surveillance fail to capture it? Findings In this cohort study of 457 950 patients with COVID-19 across 58 hospitals, validated computable phenotyping identified postacute sequelae of SARS-CoV-2 infection in 16.28% of cases, 2-fold higher than diagnostic code–based surveillance. Of identified manifestations, 89.31% represented chronic conditions, with prevalence increasing through mid-2024. Meaning Th...