A digital twin approach for simultaneous reconstruction of brain anatomy and dynamics from neural data (opens in new tab)

Author summary Autism spectrum disorder (ASD) is a common neurodevelopmental condition that affects how people communicate, learn, and interact with others. Despite decades of research, the biological mechanisms underlying ASD remain difficult to pinpoint, partly because we cannot easily study how brain structure and activity interact in patients. In this study, we developed a new approach to bridge that gap based on a digital twin: a detailed computational replica of the patient’s brain. Our...