IntAct-U-ExM enables super-resolution imaging of isoform-specific actin networks across species (opens in new tab)

A previous study in PLOS Biology developed IntAct, a tool to study isoform-specific actin localization, dynamics and molecular interactions across species. In this Update Article, IntAct is coupled with ultrastructure expansion microscopy to enable the super-resolution imaging of various actin structures in yeast and mammalian cells.