Decoding and steering spatially resolved cellular dynamics (opens in new tab)

Understanding how cells transition between states is central to biology. RNA velocity has emerged as a transformative framework for inferring future cellular states from unspliced and spliced mRNA transcripts. A new deep generative and agent‑based method can decode and manipulate cellular dynamics within native tissue by dissecting spatially resolved RNA velocity and simulating regulatory interventions, opening new opportunities to explore how tissue context shapes and potentially controls ce...