Medical Xpress

The brain's night shift: How sleep, waste clearance and dementia may be linked (opens in new tab)

Why are conditions such as chronic stress, depression, cardiovascular disease, fragmented sleep, and aging all associated with a higher risk of dementia? In a new review piece in Science, University of Rochester Medicine neuroscientist Maiken Nedergaard, MD, DMSc, proposes that many of these seemingly different conditions may converge on the same biological problem: disruption of a sleep-dependent brain rhythm that helps clear waste from the brain.

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