Eliminating cancer cells that survive KRAS inhibition: A potential way to prevent relapse (opens in new tab)

Our cells rely on tightly regulated signaling pathways to control when they grow, divide and survive. When these regulatory systems are disrupted, cells can acquire the ability to grow uncontrollably and become cancerous. One of the most important cancer-related signaling molecules is the Kirsten rat sarcoma viral oncogene homologue (KRAS), which functions like an on/off switch for cell growth.