What a 'silenced' chromosome can tell us about autoimmunity (opens in new tab)

Systemic lupus erythematosus (SLE), the most common form of lupus, is an autoimmune disorder that occurs more frequently in women. Having multiple X chromosomes has been associated with an increased risk of developing lupus; however, the reason for this link is still not fully understood and may involve how X chromosomes are regulated in female immune cells.