What FDG-PET Studies Show – ADD Resource Center (opens in new tab)

Brain imaging using fluorodeoxyglucose positron emission tomography (FDG-PET) has produced suggestive but inconsistent evidence linking ADHD to altered cerebral glucose metabolism, with the most reproducible findings implicating fronto-striatal and premotor circuits. However, results vary substantially by age, sex, task, and study design, and chronic stimulant treatment does not produce robust metabolic shifts even when symptoms clearly improve. No FDG-PET signature is currently sensitive or ...