An autonomous LLM agent platform for computational binder design and conjugation-aware prioritization of antibody drug conjugates (opens in new tab)

Large language model (LLM) agents have automated tool use in chemistry, but orchestrating multi step computational biology workflows spanning structure prediction, protein design, and covalent conjugation remains manually intensive. Here we present Open Intelligence Hub (OIH), an autonomous LLM agent platform that dynamically plans and executes 32 containerised tools for protein binder design and antibody drug conjugate (ADC) prioritization. OIH introduces tier based decision routing, ipSAE g...