CountESS: a flexible, graphical pipeline tool for deep mutational scanning analysis (opens in new tab)

Deep Mutational Scanning (DMS) experiments generate large volumes of sequencing data that must be processed through multi-step computational pipelines to yield interpretable variant scores. At least twelve dedicated tools have been published for this purpose, yet the diversity of experimental designs, scoring strategies, and software implementations has produced a fragmented landscape in which no single tool accommodates the full range of workflows encountered in practice. Here we present Cou...