DCAFA: Differential Community Abundance and Feature Analysis for Histological Images (opens in new tab)

Histological images are composed of diverse local structures such as cells, glands, or tissue patches, whose organisation and relative abundance reflect underlying biological processes. While most computational approaches focus on analysing individual features, many clinically relevant signals arise from changes in the composition of these structures rather than isolated measurements. This motivates the need for explicitly modelling how groups of similar instances vary across samples and rela...