Decoding Condition-Specific Cellular Crosstalk in Spatial Omics via Bilinear Edge Classification (opens in new tab)

Tissues are multicellular structured communities whose function emerges from a combination of individual cellular characteristics along with their corresponding spatial configuration, affecting their interactions and response patterns. During processes such as disease progression or aging, tissues can undergo structural reorganization, including changes in co-localization of different cell types, assembly or destruction of functional niches, and disruption of intercellular communication axes....