Phylogenomic coupling of F1 chemosensory and archaellum systems across archaea and monoderm bacteria (opens in new tab)

Archaellum-associated motility has been viewed as solely archaeal, yet new findings in Chloroflexota prompt a broader perspective. By analysing a curated ~22,000 NCBI reference genomes alongside 2,397 archaeal and 226 archaellum-encoding Chloroflexota genomes, this study systematically characterises the co-distribution of archaellum loci with chemosensory system (CSS) classes. Maximum-likelihood phylogeny of 3,727 F1-type CheA proteins reveals three major clades, with Clade 1 comprising ~80% ...