PXN Unlocks the Power of Public Gene Expression Data Through Cross-Technology Integration (opens in new tab)

The immense value of public gene expression repositories is constrained by the lack of compatibility among datasets generated from diverse experimental technologies. Differences in measurement scales, probe chemistries, and signal distributions create systematic discrepancies across platforms and laboratories. These inconsistencies make large-scale integrative analysis nearly impossible, even though such studies could achieve great statistical power and improved reproducibility. We introduce ...