A novel method to select Reference Proteomes in UniProt (opens in new tab)

Motivation: The ongoing revolution in genome sequencing is delivering an unprecedented number of genome assemblies to global repositories, resulting in an overwhelming amount of data imported to UniProt in the form of proteomes. To manage this growth sustainably, there is a need for a systematic workflow to select the best proteomes. Results: We propose a novel pipeline for cellular organisms to select the best Reference Proteomes, i.e. those that best represent the protein space of a species...