biorxiv.org

S2F-agent: Skill-grounded agent for Sequence-to-Function computational genomics workflows (opens in new tab)

Sequence-to-Function (S2F) foundation models are revolutionizing genomic research, yet their fragmented ecosystem severely bottlenecks practical application by incompatible inputs, outputs, and runtime environments. General-purpose coding agents lack the strict domain constraints necessary to resolve these biological intricacies safely. Here, we present s2f-agent, a skill-grounded agent orchestration system that translates open-ended genomics queries into reproducible, executable analysis. By...

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