ToxCastLite: A portable semantic evidence graph linking in vitro bioactivity, in vivo toxicity, and exposure-use context (opens in new tab)

Motivation: The ToxCast database is a valuable resource for computational toxicology and new approach methodologies (NAMs), but the approximately 100GB MySQL distribution is difficult to use for portable local analysis and cross-domain evidence mining. Many practical questions concern chemicals, in vitro bioactivity, in vivo toxicological evidence, and exposure-relevant product-use context rather than raw database keys. Results: We present ToxCastLite, a portable semantic evidence-access syst...