Transcriptomic profiling reveals multiple mechanisms of insecticide resistance in Aedes aegypti from Angola (opens in new tab)

Control of arboviruses remains heavily reliant on insecticide-based vector control targeting adult Aedes aegypti, especially during outbreaks, but the effectiveness of these tools can be compromised by insecticide resistance. While the mechanisms underlying resistance have been widely studied in Latin American and South East Asian Ae. aegypti, knowledge from African populations is limited, particularly regarding metabolic resistance. To address this knowledge gap, we sequenced the transcripto...