Ultra-efficient High Resolution 3D Reconstruction of Spatial Omics Data with Neural Transcriptomic Field (opens in new tab)

Biological tissues are inherently three-dimensional (3D) ecosystems where spatial architecture dictates cellular function. While spatial omics technologies have revolutionized molecular profiling, they are largely restricted to isolated two-dimensional (2D) tissue sections. Existing computational methods attempting to reconstruct 3D volumes from sparse slices rely heavily on local slice-to-slice interpolation, struggling to balance high-fidelity reconstruction, noise reduction, and atlas-scal...