A Multi-Epitope Vaccine Design for Human Pasteurellosis using Outer Membrane β-barrel Proteins of Pasteurella multocida (opens in new tab)

Pasteurella multocida is a facultative anaerobic, Gram-negative coccobacillus that causes pasteurellosis in companion animals (cats and dogs), livestock, and poultry. Close contact with infected animals poses a significant zoonotic risk to humans through bite wounds, scratches, licking and transfer of bodily fluids. Current treatment relies mainly on antibiotics, and the lack of a licensed human vaccine further exacerbates the challenge. In the present study, a consensus-based computational a...