Mapping the structural coverage of Arabidopsis thaliana plant developmental proteins: Insights from Experimental and AlphaFold Approaches (opens in new tab)

Background: Plant development is a multifaceted process governed by intricate protein regulatory networks. High-throughput sequencing methods have vastly expanded plant transcriptomic and proteomic datasets, yet there is a large discrepancy between structural information for plant developmental proteins and the UniProt sequence entries. Advances in X-ray crystallography, NMR spectroscopy, and Cryo-EM have enabled the determination of protein complex structures and their dynamics. AI-driven to...