Orbitofrontal-sensory cortical interactions in learning and adaptive decision-making (opens in new tab)

The orbitofrontal cortex (OFC) is a hub for value-guided decision-making, linked reciprocally with both cortical and subcortical regions. While projections from sensory areas to the OFC – and vice versa – are known to support goal-directed learning, these projections have often been studied in isolation, and their joint effect remains poorly understood. Here, we revisit these circuits through a unifying computational framework. We propose that sensory cortices send compressed task knowledge t...