High Altitude Populations Exhibit Features of Accelerated Immune Aging (opens in new tab)

You may recall the epidemiological study indicating that populations at moderate altitude exhibit better long term health and a lower risk of age-related disease. The authors of that study suggested that this is because a greater level physical activity is involved in day to day activities in hilly regions, but this hypothesis is far from proven. Going beyond moderate elevation, we enter the realm of mild hypoxia as oxygen levels fall with increasing height above sea level. Interestingly, evi...