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PEPITEM as a Potential Therapy for Autoimmune Arthritis (opens in new tab)

PEPITEM is a circulating peptide involved in resolution of inflammation and reduction of chronic inflammation. Levels of PEPITEM decline with age, which is one of the reasons why inflammatory athritis becomes worse with age, in that this inhibitory mechanism declines in effectiveness. Studies in animal models have shown that injection of synthetic PEPITEM can improve symptoms; an example of this sort of work is noted here. Inflammatory arthritis is a group of diseases, including rheumatoid ar...

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