Phosphatidylcholine Synthesis Declines with Age to Contribute to Mitochondrial Dysfunction (opens in new tab)

Every cell contains hundreds of mitochondria, the descendants of ancient symbiotic bacteria that evolved to become components of the cell. Along the way most of the original mitochondrial genome migrated into the cell nucleus, leaving only a small remnant genome inside mitochondria. The primary task undertaken by mitochondria is the production of the chemical energy store molecule adenosine triphosphate (ATP), used to power cell activities. This is produced via energetic processes that also p...